Can knowledge be a burden rather than being a benefit?

Knowledge can take you to many things in life, it helps you figure things out with common sense, and gives you a better picture of the way life works. Knowledge can be useful for many things. Such as survival, not having a knowledge of wild life or surviving the wild, will end up killing you in a matter of days. Sure know it all's are always the most annoying when it comes to knowing a billion things, but in realidy it's not all that bad although when it comes to showing off then that's a different situation. Knowledge has effected famous people like Albert Einstein, Thomas Edison, and so much more inventors and scientists that had success in life. Knowledge is a burden but it's not something to be ashamed of, so in a way knowledge is beneficial if used well.